Temperature effects on synaptic transmission and neuronal function in the visual thalamus.

ABSTRACT: Numerous neuronal properties including the synaptic vesicle release process, neurotransmitter receptor complement, and postsynaptic ion channels are involved in transforming synaptic inputs into postsynaptic spiking. Temperature is a significant influencer of neuronal function and synaptic integration. Changing temperature can affect neuronal physiology in a diversity of ways depending on how it affects different members of the cell's ion channel complement. Temperature's effects on neuronal function are critical for pathological states such as fever, which can trigger seizure activity, but are also important in interpreting and comparing results of experiments conducted at room vs physiological temperature. The goal of this study was to examine the influence of temperature on synaptic pro

SUBMITTER: Van Hook MJ 

PROVIDER: S-EPMC7192487 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature