Tracing the evolution of fatty acid-binding proteins (FABPs) in organisms with a heterogeneous fat distribution.

ABSTRACT: The distribution of fat among both invertebrate and vertebrate groups is heterogeneous. Studies have shown that fatty acid-binding proteins (FABPs), which mainly bind and transport fatty acids, play important roles in the regulation of fat storage and distribution. However, the systematic and genome-wide investigation of FABP genes in organisms with a heterogeneous fat distribution remains in its infancy. The availability of the complete genomes of Caenorhabditis elegans, Callorhinchus milii, and other organisms with a heterogeneous fat distribution allowed us to systematically investigate the gene structure and phylogeny of FABP genes across a wide range of phyla. In this study, we analyzed the number, structure, chromosomal location, and phylogeny of FABP genes in 18 organisms from C. el

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC7193176 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature