Ontology highlight
ABSTRACT:
SUBMITTER: Janjua S
PROVIDER: S-EPMC7193764 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Janjua Sadia S Fortescue Rebecca R Poole Phillippa P
The Cochrane database of systematic reviews 20200501
<h4>Background</h4>Chronic obstructive pulmonary disease (COPD) is associated with cough, sputum production or dyspnoea, and a reduction in lung function, quality of life, and life expectancy. Apart from smoking cessation, no other treatments that slow lung function decline are available. Roflumilast and cilomilast are oral phosphodiesterase-4 (PDE₄) inhibitors proposed to reduce the airway inflammation and bronchoconstriction seen in COPD. This Cochrane Review was first published in 2011, and w ...[more]