Pregnancy phthalate metabolite concentrations and infant birth weight by gradations of maternal glucose tolerance.

ABSTRACT:

Background

Higher birth weight is an important adverse outcome associated with hyperglycemia in pregnancy. Recent studies suggest that phthalate exposure is associated with elevated glucose levels in pregnant women, with implications for higher birth weight in the offspring. No study to date has investigated the association between prenatal phthalate exposure on infant high birth weight accounting for the range of pregnancy glucose levels.

Methods

A total of 350 women participating in an ongoing pregnancy cohort had data available on urinary phthalate metabolite concentrations at up to four time points across pregnancy. Urinary phthalate metabolites were averaged across pregnancy and log-transformed, specific gravity-adjusted and analyzed in quartiles. Birth weight was exami

SUBMITTER: Noor N 

PROVIDER: S-EPMC7193985 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature