Correlation between salivary estrogen levels and oral epithelial cytokeratin 5 expression.

ABSTRACT: Background: Estrogen expression levels may be associated with age and may affect keratinization of the hard palate. Keratinized epithelium expresses cytokeratin 5 and 14 in the basal layer. The aim of this study was to determine the correlation between the levels of salivary estrogen and number of cytokeratin 5-positive oral epithelial cells. Methods: A total of 30 female subjects were recruited and divided into children, adults and elderly (N=10 per group). Salivary estrogen levels and cytokeratin 5-expressing oral epithelial cells were assessed using ELISA and immunohistological methods, respectively. Data were analyzed using ANOVA with post hoc LSD test and Pearson's correlation coefficient. Results: The results showed that both the number of cytokeratin 5-positive

SUBMITTER: Handajani J 

PROVIDER: S-EPMC7194496 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature