Impaired systolic function by strain imaging in heart failure with preserved ejection fraction.

ABSTRACT:

Objectives

This study sought to determine the frequency and magnitude of impaired systolic deformation in heart failure with preserved ejection fraction (HFpEF).

Background

Although diastolic dysfunction is widely considered a key pathophysiologic mediator of HFpEF, the prevalence of concomitant systolic dysfunction has not been clearly defined.

Methods

We assessed myocardial systolic and diastolic function in 219 HFpEF patients from a contemporary HFpEF clinical trial. Myocardial deformation was assessed using a vendor-independent 2-dimensional speckle-tracking software. The frequency and severity of impaired deformation was assessed in HFpEF, and compared to 50 normal controls free of cardiovascular disease and to 44 age- and sex-matched hypertensive patients with d

SUBMITTER: Kraigher-Krainer E 

PROVIDER: S-EPMC7195816 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature