The predictive value of PRDM2 in solid tumor: a systematic review and meta-analysis.

ABSTRACT:

Background

Many studies have reported the presence of Positive Regulatory/Su(var)3-9, Enhancer-of-zeste and Trithorax Domain 2 (PRDM2) downregulation in cancer. However, its potential as a diagnostic biomarker is still unclear. Hence, a systematic review and meta-analysis were conducted to address this issue.

Introduction

As of 2018, cancer has become the second leading cause of death worldwide. Thus, cancer control is exceptionally vital in reducing mortality. One such example is through early diagnosis of cancer using tumor biomarkers. Having a function as a tumor suppressor gene (TSG), PRDM2 has been linked with carcinogenesis in several solid tumor. This study aims to assess the relationship between PRDM2 downregulation and solid tumor, its relationship wit

SUBMITTER: Tanadi C 

PROVIDER: S-EPMC7195840 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature