Modeling transcranial electrical stimulation in the aging brain.

ABSTRACT:

Background

Varying treatment outcomes in transcranial electrical stimulation (tES) recipients may depend on the amount of current reaching the brain. Brain atrophy associated with normal aging may affect tES current delivery to the brain. Computational models have been employed to compute predicted tES current inside the brain. This study is the largest study that uses computational models to investigate tES field distribution in healthy older adults.

Methods

Individualized head models from 587 healthy older adults (mean = 73.9years, 51-95 years) were constructed to create field maps. Two electrode montages (F3-F4, M1-SO) with 2 mA input current were modeled using ROAST with modified codes. A customized template of healthy older adults, the UFAB-587, was created from the sam

SUBMITTER: Indahlastari A 

PROVIDER: S-EPMC7196025 | biostudies-literature | 2020 May - Jun

REPOSITORIES: biostudies-literature