Risk Factors for Cognitive Impairment in Patients with Type 2 Diabetes.

ABSTRACT:

Objectives

To investigate the risk factors for cognitive impairment in Chinese type 2 diabetes mellitus (T2DM) patients of advanced age and to identify effective biomarkers of mild cognitive impairment (MCI) in these patients.

Methods

Chinese T2DM patients (n = 120) aged 50-70 years were divided into groups with impaired (mild, moderate, and severe) and normal cognitive function based on Montreal Cognitive Assessment and Mini-Mental State Examination scores. Data regarding demographic characteristics, clinical features of diabetes, biochemical markers, and metabolomics were collected.

Results

Age, educational level, duration of diabetes, fasting blood glucose (FBG), HbA1c, total cholesterol (TC), triglyceride (TG), and 24-hour urine protein were significantly a

SUBMITTER: Sun L 

PROVIDER: S-EPMC7196145 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature