Low grade albuminuria as a risk factor for subtypes of stroke - the HUNT Study in Norway.

ABSTRACT: BACKGROUND AND PURPOSE:Albuminuria is a marker for endothelial dysfunction and knowledge on its association with stroke and stroke subtypes are limited. METHODS:Corresponding data from 7261 participants of the population-based HUNT2 study (1995-1997) was linked with hospital records, identified all patients registered and diagnosed with a first-time stroke. Each diagnosis was validated by reviewal of the medical record appertaining to the individual. We then applied Cox proportional hazard models to estimate the hazard ratios (HRs) for the association between albuminuria (measured as albumin-to-creatinine-ratio, ACR) and diagnosis of stroke and stroke subtypes. RESULTS:703 (9.7%) participants developed a first ischemic stroke during a median follow-up of 15 years. Higher albuminuria was as

SUBMITTER: Horn JW 

PROVIDER: S-EPMC7196218 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature