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Infections in children with autism spectrum disorder: Study to Explore Early Development (SEED).


ABSTRACT: Immune system abnormalities have been widely reported among children with autism spectrum disorder (ASD), which may increase the risk of childhood infections. The Study to Explore Early Development (SEED) is a multisite case-control study of children aged 30-69 months, born in 2003-2006. Cases are children previously diagnosed and newly identified with ASD enrolled from education and clinical settings. Children with a previously diagnosed non-ASD developmental condition were included in the developmental delay/disorder (DD) control group. The population (POP) control group included children randomly sampled from birth certificates. Clinical illness from infection during the first 28 days ("neonatal," from medical records) and first three years of life (caregiver report) in cases was compar

SUBMITTER: Sabourin KR 

PROVIDER: S-EPMC7197040 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature