Quantitative three-dimensional ultrashort echo time cones imaging of the knee joint with motion correction.

ABSTRACT: Knee degeneration involves all the major tissues in the joint. However, conventional MRI sequences can only detect signals from long T2 tissues such as the superficial cartilage, with little signal from the deep cartilage, menisci, ligaments, tendons and bone. It is highly desirable to develop new sequences that can detect signal from all major tissues in the knee. We aimed to develop a comprehensive quantitative three-dimensional ultrashort echo time (3D UTE) cones imaging protocol for a truly "whole joint" evaluation of knee degeneration. The protocol included 3D UTE cones actual flip angle imaging (3D UTE-Cones-AFI) for T₁ mapping, multiecho UTE-Cones with fat suppression for T₂ * mapping, UTE-Cones with adiabatic T_1ρ (AdiabT_1ρ ) preparation f

SUBMITTER: Wu M 

PROVIDER: S-EPMC7197345 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature