Genus Bupleurum: a review of its phytochemistry, pharmacology and modes of action.

ABSTRACT:

Objectives

Radix Bupleuri represents one of the most successful and widely used herbal drugs in Asia for treatment of many diseases over the past 2000 years. Thorough studies have been carried out on many species of this genus and have generated immense data about the chemical composition and corresponding biological activity of extracts and isolated secondary metabolites. In this work, we review the chemistry and pharmacology of the genus Bupleurum and explore the relationships between the pharmacological effects and the chemical composition of these drugs.

Key findings

Early studies on the genus Bupleurum had focused only on the traditional uses of the plants in the treatment of inflammatory disorders and infectious diseases. After chemical profiling, several groups of sec

SUBMITTER: Ashour ML 

PROVIDER: S-EPMC7197585 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature