The use of perioperative chemotherapy in patients undergoing radical cystectomy for bladder cancer in Quebec, Canada, 2000-2016.

ABSTRACT:

Introduction

Despite its proven benefit, studies have reported poor use of perioperative chemotherapy (POC) in bladder cancer patients undergoing radical cystectomy (RC). We evaluated POC use in Quebec between January 2000 and September 2016.

Methods

Using provincial health administrative databases, data were retrospectively collected from patients from two years before RC until December 2016 or death. Logistic regression was used to identify variables predicting POC use. Survival analyses were conducted using Cox regression. Analyzed covariates were age, sex, comorbidities, year of RC, residence and hospital region, distance to hospital, hospital type and size, and hospital's and surgeon's RC volume.

Results

A total of 790/4656 patients (17.0%) received POC. Neoadjuv

SUBMITTER: Wissing MD 

PROVIDER: S-EPMC7197966 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature