Norovirus Activity and Genotypes in Sporadic Acute Diarrhea in Children in Shanghai During 2014-2018.

ABSTRACT:

Background

Based on the impact public health of norovirus and the current progress in norovirus vaccine development, it is necessary to continuously monitor the epidemiology of norovirus infection, especially in children who are more susceptible to norovirus.

Objectives

To monitor the activity and genotypes of norovirus infection in sporadic diarrhea in Shanghainese children during 2014-2018.

Study design

Acute diarrheal cases were prospectively enrolled in the outpatient setting. Real-time reverse transcription-polymerase chain reaction was used for screening norovirus GI and GII genogroups. Dual norovirus genotypes were identified based on the partial capsid and polymerase gene sequences.

Results

Of the 3422 children with diarrhea, 510 (14.9%) were positive f

SUBMITTER: Wang X 

PROVIDER: S-EPMC7198057 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature