Maternal blood metal and metalloid concentrations in association with birth outcomes in Northern Puerto Rico.

ABSTRACT:

Background

In previous studies, exposures to heavy metals such as Pb and Cd have been associated with adverse birth outcomes; however, knowledge on effects at low levels of exposure and of other elements remain limited.

Method

We examined individual and mixture effects of metals and metalloids on birth outcomes among 812 pregnant women in the Puerto Rico Testsite for Exploring Contamination Threats (PROTECT) cohort. We measured 16 essential and non-essential metal(loid)s in maternal blood collected at 16-20 and 24-28 weeks gestation. We used linear and logistic regression to independently examine associations between geometric mean (GM) concentrations of each metal across visits and gestational age, birthweight z-scores, preterm birth, small for gestational age (SGA), and la

SUBMITTER: Ashrap P 

PROVIDER: S-EPMC7198231 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature