Early-Onset Neonatal Sepsis 2015 to 2017, the Rise of Escherichia coli, and the Need for Novel Prevention Strategies.

ABSTRACT:

Importance

Early-onset sepsis (EOS) remains a potentially fatal newborn condition. Ongoing surveillance is critical to optimize prevention and treatment strategies.

Objective

To describe the current incidence, microbiology, morbidity, and mortality of EOS among a cohort of term and preterm infants.

Design, setting, and participants

This prospective surveillance study included a cohort of infants born at a gestational age (GA) of at least 22 weeks and birth weight of greater than 400 g from 18 centers of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network from April 1, 2015, to March 31, 2017. Data were analyzed from June 14, 2019, to January 28, 2020.

Main outcomes and measures

Early-onset sepsis defined

SUBMITTER: Stoll BJ 

PROVIDER: S-EPMC7199167 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature