Increased risk of maternal and neonatal complications in hormone replacement therapy cycles in frozen embryo transfer.

ABSTRACT:

Background

The endometrial preparation during frozen embryo transfer (FET) can be performed by natural cycle (NC), hormone replacement therapy (HRT) cycle and cycle with ovulation induction (OI). Whether different FET preparation protocols can affect maternal and neonatal outcomes is still inconclusive.

Methods

This was a retrospective cohort study that included 6886 women who delivered singleton live birth babies after 28 weeks of pregnancy underwent FET from January, 2015 to July, 2018. Women were divided into three groups according to the protocols used for endometrial preparation during FET: NC group (N = 4727), HRT group (N = 1642) and OI group (N = 517).

Results

After adjusting for the effect of age, body mass index (BMI), irregular menstruation, antral follicle

SUBMITTER: Zong L 

PROVIDER: S-EPMC7199365 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature