Optimizing the deployment of ultra-low volume and targeted indoor residual spraying for dengue outbreak response.

ABSTRACT: Recent years have seen rising incidence of dengue and large outbreaks of Zika and chikungunya, which are all caused by viruses transmitted by Aedes aegypti mosquitoes. In most settings, the primary intervention against Aedes-transmitted viruses is vector control, such as indoor, ultra-low volume (ULV) spraying. Targeted indoor residual spraying (TIRS) has the potential to more effectively impact Aedes-borne diseases, but its implementation requires careful planning and evaluation. The optimal time to deploy these interventions and their relative epidemiological effects are, however, not well understood. We used an agent-based model of dengue virus transmission calibrated to data from Iquitos, Peru to assess the epidemiological effects of these interventions under differing strategies for d

SUBMITTER: Cavany SM 

PROVIDER: S-EPMC7200023 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature