DNA-PAINT super-resolution imaging data of surface exposed active sites on particles.

ABSTRACT: Surface functionalization with targeting ligands confers to nanomaterials the ability of selectively recognize a biological target. Therefore, a quantitative characterization of surface functional molecules is critical for the rational development of nanomaterials-based applications, especially in nanomedicine research. Single-molecule localization microscopy can provide visualization of surface molecules at the level of individual particles, preserving the integrity of the material and overcoming the limitations of analytical methods based on ensemble averaging. Here we provide single-molecule localization data obtained on streptavidin-coated polystyrene particles, which can be exploited as a model system for surface-functionalized materials. After loading of the active sites of streptavi

SUBMITTER: Delcanale P 

PROVIDER: S-EPMC7200214 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature