Impact and Outcomes of Pretreatment Total Serum Testosterone on Localized Prostate Cancer Patients.

ABSTRACT:

Purpose

To investigate how pretreatment testosterone levels correlate with progression-free survival, metastasis-free survival, and overall survival in a propensity-adjusted localized prostate cancer population.

Methods

Men diagnosed with clinical NCCN-risk stratified very-low, low, intermediate, high, and/or very-high risk prostate cancer who had a baseline total serum testosterone level≥100 ng/dl measured within the 100 days preceding the first definitive therapy were identified from our prospectively gathered institutional database. Cohorts below (100-239 ng/dl), within (240-593 ng/dl), or above (594 + ng/dl) one standard deviation from the mean testosterone level (416 ng/dl) were used for comparison. Progression-free, metastasis-free, and overall survival were evaluated.

SUBMITTER: Usera BM 

PROVIDER: S-EPMC7201500 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature