Adjusting for comorbidity in incidence-based DALY calculations: an individual-based modeling approach.

ABSTRACT:

Background

The co-occurrence of two or more medical conditions in the same individual is not uncommon. If disability-adjusted life year (DALY) calculations are carried out for each condition separately, multimorbidity may lead to an overestimation of the morbidity component, the Years Lived with Disability (YLD). Adjusting for comorbidity may be straightforward if all symptoms have same onset and duration; however, when the comorbid health states occur at different time points, an analytical solution to the comorbidity problem becomes more complex. The aim of this study was to develop an individual-based modelling (IBM) approach to adjust incidence-based disease burden estimation for multimorbidity that allows simulating hypothetical individuals and tracking their disease history,

SUBMITTER: McDonald SA 

PROVIDER: S-EPMC7201540 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature