Long-term effectiveness of catheter ablation in patients with atrial fibrillation and heart failure.

ABSTRACT:

Aims

Randomized trials suggest reductions in all-cause mortality and heart failure (HF) rehospitalizations with catheter ablation (CA) in patients with atrial fibrillation (AF) and HF. Whether these results can be replicated in a real-world population with long-term follow-up or varies over time is unknown. We sought to evaluate the long-term effectiveness of CA in reducing the incidence of all-cause mortality, HF hospitalizations, stroke, and major bleeding in AF-HF patients.

Methods and results

In a cohort of patients newly diagnosed with AF-HF in Quebec, Canada (2000-2017), CA patients were matched 1:2 to controls on time and frequency of hospitalizations. Confounders were controlled for using inverse probability of treatment weighting. Multivariable Cox models adjusted f

SUBMITTER: Samuel M 

PROVIDER: S-EPMC7203635 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature