Genome-wide association analyses identify known and novel loci for teat number in Duroc pigs using single-locus and multi-locus models.

ABSTRACT:

Background

More teats are necessary for sows to nurse larger litters to provide immunity and nutrient for piglets prior to weaning. Previous studies have reported the strong effect of an insertion mutation in the Vertebrae Development Associated (VRTN) gene on Sus scrofa chromosome 7 (SSC7) that increased the number of thoracic vertebrae and teat number in pigs. We used genome-wide association studies (GWAS) to map genetic markers and genes associated with teat number in two Duroc pig populations with different genetic backgrounds. A single marker method and several multi-locus methods were utilized. A meta-analysis that combined the effects and P-values of 34,681 single nucleotide polymorphisms (SNPs) that were common in the results of single marker GWAS of American and Canadian D

SUBMITTER: Zhuang Z 

PROVIDER: S-EPMC7204245 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature