Association of LTF, ENAM, and AMELX polymorphisms with dental caries susceptibility: a meta-analysis.

ABSTRACT:

Background

This meta-analysis evaluated the association of LTF, ENAM, and AMELX polymorphisms with dental caries susceptibility.

Methods

We searched the Scopus, PubMed/Medline, Web of Science, and Cochrane Library databases to retrieve articles published by October 2019. Review Manager 5.3 software was used to estimate the odds ratios (ORs) and 95% confidence intervals (CIs). The results of publication bias tests were retrieved by Comprehensive Meta-Analysis 2.0 software.

Results

A total of 150 relevant records were identified; out of which, 16 were entered into the analysis (4 studies assessed LTF, 11 ENAM, and 11 AMELX polymorphisms). Of all polymorphisms, there was a significant association only between ENAM rs3796704 polymorphism and dental caries susceptibility.

SUBMITTER: Sharifi R 

PROVIDER: S-EPMC7204276 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature