Ontology highlight
ABSTRACT:
SUBMITTER: Ryu SY
PROVIDER: S-EPMC7204536 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Analytical chemistry 20190815 17
By circumventing the need for a pure colony, MALDI-TOF mass spectrometry of bacterial membrane glycolipids (lipid A) has the potential to identify microbes more rapidly than protein-based methods. However, currently available bioinformatics algorithms (e.g., dot products) do not work well with glycolipid mass spectra such as those produced by lipid A, the membrane anchor of lipopolysaccharide. To address this issue, we propose a spectral library approach coupled with a machine learning technique ...[more]