Facedown Positioning Following Surgery for Large Full-Thickness Macular Hole: A Multicenter Randomized Clinical Trial.

ABSTRACT:

Importance

The value of facedown positioning following surgery for large full-thickness macular holes is unknown.

Objective

To determine whether advice to position facedown postoperatively improves the outcome for large macular holes.

Design, setting, and participants

This randomized, parallel group superiority trial with 1:1 randomization stratified by site with 3 months' follow-up was conducted at 9 sites across the United Kingdom and included participants with an idiopathic full-thickness macular hole of at least 400 μm minimum linear diameter and a duration of fewer than 12 months. All participants had vitrectomy surgery with peeling of the internal limiting membrane and injection of perfluoropropane (14%) gas, with or without simultaneous surgery for cataract.

SUBMITTER: Pasu S 

PROVIDER: S-EPMC7206530 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature