Renin-Angiotensin-Aldosterone System Inhibitors and Risk of Covid-19.

ABSTRACT:

Background

There is concern about the potential of an increased risk related to medications that act on the renin-angiotensin-aldosterone system in patients exposed to coronavirus disease 2019 (Covid-19), because the viral receptor is angiotensin-converting enzyme 2 (ACE2).

Methods

We assessed the relation between previous treatment with ACE inhibitors, angiotensin-receptor blockers, beta-blockers, calcium-channel blockers, or thiazide diuretics and the likelihood of a positive or negative result on Covid-19 testing as well as the likelihood of severe illness (defined as intensive care, mechanical ventilation, or death) among patients who tested positive. Using Bayesian methods, we compared outcomes in patients who had been treated with these medications and in untreated pat

SUBMITTER: Reynolds HR 

PROVIDER: S-EPMC7206932 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature