The therapeutic effect of high-volume hemofiltration on sepsis: a systematic review and meta-analysis.

ABSTRACT:

Background

Sepsis remains the leading cause of death in the intensive care unit (ICU), despite the treatment of sepsis has progressed. As a mode in continuous renal replacement therapy (CRRT), continuous veno-venous hemofiltration (CVVH) has been widely used in the treatment of sepsis. Whether high ultrafiltrate volume in CVVH is beneficial for sepsis survival remains controversial. We performed a systematic review and meta-analysis to evaluate the treatment effect of high-volume hemofiltration (HVHF) on sepsis.

Methods

A systematic search was conducted on the Medline, Embase, and Cochrane library to June 21, 2019, the keywords included "sepsis" "continuous blood purification" "continuous renal replacement therapy" "continuous veno-venous hemofiltration" and "continuous veno

SUBMITTER: Yin F 

PROVIDER: S-EPMC7210131 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature