Characteristics of 43 multiple auricular deformity case families and auricle morphology in 463 microtia patients in South China.

ABSTRACT:

Background

Earlier studies have suggested that microtia is a genetic disease with a worldwide incidence of microtia is between 0.83/10,000 and 17.40/10,000. For microtia, auricle morphology is the most crucial characteristic. However, no studies have been performed to characterize the genetic similarity of microtia and auricle morphology similarity. For the sporadic patients, the relationship between the gestational age of parents and the incidence of microtia is unclear. To obtain the characteristics of auricular deformity multiple case family (AD-MCF) and clarify the relationship between genetic similarity and auricle morphology similarity in AD-MCF.

Methods

This study included 463 AD patients who were diagnosed by Sun Yat-sen Memorial Hospital, Sun Yat-sen University, fro

SUBMITTER: Zhang HS 

PROVIDER: S-EPMC7210143 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature