The diagnostic yield of closed needle pleural biopsy in exudative pleural effusion: a retrospective 10-year study.

ABSTRACT:

Background

Pleural effusion is a common presentation in clinical practice. About 40% of exudative pleural effusion is unable to be diagnosed through thoracentesis, and closed pleural biopsy (CPB) is needed. This study was designed to investigate the diagnostic yield of CPB in exudative pleural effusion.

Methods

This was a retrospective 10-year study of patients with unexplained exudative pleural effusion who underwent CPB in two centers. Malignant pleural effusion (MPE) was diagnosed when there was histopathological evidence of pleural tissue, pulmonary tissue, or pleural fluid. Tuberculous pleural effusion (TPE) was confirmed when granuloma or coagulative necrosis was observed in pleural tissue, Ziehl-Neelsen acid-fast staining was positive, or adenosine deaminase (ADA) in

SUBMITTER: Zhang T 

PROVIDER: S-EPMC7210145 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature