New peptidendrocins and anticancer chartreusin from an endophytic bacterium of Dendrobium officinale.

ABSTRACT:

Background

Endophyte has now become a potential source for the discovery of novel natural products, as they participate in biochemical pathways of their hosts and produce analogous or novel bioactive compounds. As an epiphytic plant, Dendrobium officinale is one of precious Chinese medicines with various activities. It is well known for containing diverse endophytes, but so far not much is known about their secondary metabolites.

Methods

the plant tissues were cut and cultured on agar plates to isolate and purify the endophytic bacteria from Dendrobium officinale. Taxonomical identification of strains was performed by 16s rRNA. At the same time, the crude extracts of the strains were tested for antibacterial and cytotoxic activities to screen out one endophyte,

SUBMITTER: Zhao H 

PROVIDER: S-EPMC7210183 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature