Real-world impact of postmastectomy radiotherapy in T1-2 breast cancer with one to three positive lymph nodes.

ABSTRACT:

Background

The utility of postmastectomy radiotherapy (PMRT) in breast cancer patients with T1-2 (tumor size ≤5 cm) and N1 (one to three lymph nodes involved) disease remains controversial. The aim of this population-based study was to investigate the effectiveness of PMRT in this patient subset in the current clinical practice.

Methods

We included T1-2N1 breast cancer patients treated with mastectomy from 2004 to 2012 using the data form the Surveillance, Epidemiology, and End Results program. The association of PMRT administration with breast cancer-specific survival was determined using multivariable Cox analysis.

Results

We identified 10,248 patients of this study, including 3,725 (36.3%) received PMRT and 6,523 (63.7%) patients did not receive PMRT. Use of PMRT s

SUBMITTER: Li FY 

PROVIDER: S-EPMC7210210 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature