How obsessive-compulsive and bipolar disorders meet each other? An integrative gene-based enrichment approach.

ABSTRACT:

Background

The novel approaches to psychiatric classification assume that disorders, contrary to what was previously thought, are not completely separate phenomena. In this regard, in addition to symptom-based criteria, disturbances are also considered on the basis of lower level components. With this viewpoint, identifying common biochemical markers would be beneficial in adopting a comprehensive strategy for prevention, diagnosis and treatment.

Main body

One of the problematic areas in clinical settings is the coexistence of both obsessive-compulsive disorder (OCD) and bipolar disorder (BD) that is challenging and difficult to manage. In this study, using a system biologic approach we aimed to assess the interconnectedness of OCD and BD at different levels. Gene Set Enrich

SUBMITTER: Hamidian S 

PROVIDER: S-EPMC7211339 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature