A comprehensive metabolic profiling of the metabolically healthy obesity phenotype.

ABSTRACT:

Background

The ever-increasing prevalence of obesity constitutes a major health problem worldwide. A subgroup of obese individuals has been described as "metabolically healthy obese" (MHO). In contrast to metabolically unhealthy obese (MUO), the MHO phenotype has a favorable risk profile. Despite this, the MHO phenotype is still sub-optimally characterized with respect to a comprehensive risk assessment. Our aim was to increase the understanding of metabolic alterations associated with healthy and unhealthy obesity.

Methods

In this cross-sectional study, men and women (18-70 years) with obesity (body mass index (BMI) ≥ 30 kg/m²) or normal weight (NW) (BMI ≤ 25 kg/m²) were classified with MHO (n = 9), MUO (n = 10) or NW (n = 11) according to weight, lipi

SUBMITTER: Telle-Hansen VH 

PROVIDER: S-EPMC7211343 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature