Magnetic nanoparticles assisted dispersive liquid-liquid microextraction of chloramphenicol in water samples.

ABSTRACT: This work describes the development of a new methodology based on magnetic nanoparticles assisted dispersive liquid-liquid microextraction (DLLME-MNPs) for preconcentration and extraction of chloramphenicol (CAP) antibiotic residues in water. The approach is based on the use of decanoic acid as the extraction solvent followed by the application of MNPs to magnetically retrieve the extraction solvent containing the extracted CAP. The coated MNPs were then desorbed with methanol, and the clean extract was analysed using ultraviolet-visible spectrophotometry. Several important parameters, such as the amount of decanoic acid, extraction time, stirring rate, amount of MNPs, type of desorption solvent, salt addition and sample pH, were evaluated and optimized. Optimum parameters were as follows:

SUBMITTER: Saad SM 

PROVIDER: S-EPMC7211875 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature