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Oral antiplatelet therapy in the elderly undergoing percutaneous coronary intervention: an umbrella review.


ABSTRACT: Percutaneous coronary intervention has become a mainstay in the management of coronary artery disease. While initially advanced age was considered a relative contraindication to invasive management of coronary artery disease, current cardiovascular practice stands solidly on an early invasive approach for elderly patients, typically based on radial access and drug-eluting stent implantation. Since the advent of coronary stents, oral antiplatelet therapy has proved crucial to maximize the benefits and minimize the risks of stenting, and this holds even truer in older patients rather than in younger ones. Indeed, the elderly is typically at higher risk of thrombotic events as well as bleeding complications, and thus careful decision making must be exercised to prescribe the most appropriate

SUBMITTER: Biondi-Zoccai G 

PROVIDER: S-EPMC7212118 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature