Differentiating thymoma from thymic cyst in anterior mediastinal abnormalities smaller than 3 cm.

ABSTRACT:

Background

Computed tomography (CT) screening for lung cancer has led to frequent findings of small anterior mediastinal masses. It is very hard to distinguish small thymomas from thymic cysts. The objective of this study was to develop a clinical model for predicting small thymomas (<3 cm) in asymptomatic patients.

Methods

Patients who underwent thymectomy for anterior mediastinal masses between 2004 and 2016 were included. All preoperative CT scans (pre- and post-enhanced) were retrospectively reviewed. Size, location, contour, shape, presence of calcification, and enhancement [Hounsfield units (HU)] were evaluated. A nomogram was built based on the predictive factors. For external validation, patients undergoing thymectomy in 2017 were enrolled and thymoma prediction was

SUBMITTER: Jung W 

PROVIDER: S-EPMC7212157 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature