Effects of Statins on Lipid Profile of Kidney Transplant Recipients: A Meta-Analysis of Randomized Controlled Trials.

ABSTRACT:

Objective

To assess the benefits of statins on lipid profile in kidney transplant recipients via a meta-analysis.

Methods

We systematically identified peer-reviewed clinical trials, review articles, and treatment guidelines from PubMed, Embase, the Cochrane Library, Wanfang, Chinese National Knowledge Infrastructure (CNKI), SinoMed (CBM), and Chongqing VIP databases from inception to April 2019. In the analysis, only randomized controlled clinical trials performed in human were included.

Results

Eight articles were included in the analysis, involving 335 kidney transplant recipients who received statins and 350 kidney transplant patients as the control group. Results revealed that statins improved the lipid profile of kidney transplant recipients. Specifically, statin

SUBMITTER: Huang X 

PROVIDER: S-EPMC7212277 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature