Use of a Long-Acting Opioid Microsphere Formulation to Overcome Difficulties in Swallowing Pain Medication.

ABSTRACT:

Purpose

Xtampza ER^® (XER) is a long-acting oxycodone formulation which was designed to be abuse-deterrent and to overcome capsule-swallowing issues. This pilot study evaluated the effectiveness of XER at reducing swallowing difficulty while providing effective analgesia in the setting of chronic pain.

Subjects and methods

Eleven subjects with chronic pain who reported pill-swallowing difficulty were enrolled in a 6-week uncontrolled open-label pilot study in which their prescribed daily opioid medication was converted to XER. Swallowing difficulty, pain intensity, opioid satisfaction, and secondary indicators of pain response were recorded for subjects throughout the study.

Results

Both swallowing difficulty and opioid satisfaction (XER vs baseline opioid)

SUBMITTER: Anderson N 

PROVIDER: S-EPMC7212775 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature