Male hormone-interfering drugs and meningioma development.

ABSTRACT:

Background

Extremely strong associations between male hormone-interfering drugs and meningiomas have been reported in two previous studies, but these findings are limited by small size of the study populations and possibly by surveillance- and selection bias. Thus, such possible and indeed very interesting association must be investigated in a large, unselected cohort. Accordingly, the aim of this study was to determine whether patients exposed to male hormone-interfering drugs had a higher risk of meningioma development in a nationwide cohort study.

Methods

A retrospective Danish nationwide cohort study with follow-up from January 1, 1996 to December 31, 2016. Exposure was use of male hormone-interfering drugs (5-α-reductase-inhibitors, luteinizing hormone-releasing hormone

SUBMITTER: Giraldi L 

PROVIDER: S-EPMC7212874 | biostudies-literature | 2019 May-Dec

REPOSITORIES: biostudies-literature