Association Between Stress and Coping with DNA Methylation of Blood Pressure-Related Genes Among African American Women.

ABSTRACT: Exposure to psychosocial stress and employment of high effort coping strategies have been identified as risk factors that may partially explain the high prevalence of hypertension among African Americans. One biological mechanism through which stress and coping may affect risk of hypertension is via epigenetic modifications (e.g. DNA methylation) in blood pressure-related genes, however this area remains understudied in African Americans. We used data from the ongoing Intergenerational Blood Pressure Study (InterGEN), a longitudinal study designed to investigate factors that contribute to hypertension risk in African American women (n=120) and their young children, to investigate the association between stress overload, problem solving coping, avoidance coping, and social support coping wi

SUBMITTER: Brown KM 

PROVIDER: S-EPMC7213592 | biostudies-literature | 2019 Jan-Dec

REPOSITORIES: biostudies-literature