CoryneRegNet 7, the reference database and analysis platform for corynebacterial gene regulatory networks.

ABSTRACT: We present the newest version of CoryneRegNet, the reference database for corynebacterial regulatory interactions, available at www.exbio.wzw.tum.de/coryneregnet/. The exponential growth of next-generation sequencing data in recent years has allowed a better understanding of bacterial molecular mechanisms. Transcriptional regulation is one of the most important mechanisms for bacterial adaptation and survival. These mechanisms may be understood via an organism's network of regulatory interactions. Although the Corynebacterium genus is important in medical, veterinary and biotechnological research, little is known concerning the transcriptional regulation of these bacteria. Here, we unravel transcriptional regulatory networks (TRNs) for 224 corynebacterial strains by utilizing genome-scale

SUBMITTER: Parise MTD 

PROVIDER: S-EPMC7214426 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature