Thenar oxygen saturation (StO₂) alterations during a spontaneous breathing trial predict extubation failure.

ABSTRACT:

Background

Weaning from mechanical ventilation (MV) is a cardiovascular stress test. Monitoring the regional oxygenation status has shown promising results in predicting the tolerance to spontaneously breathe in the process of weaning from MV. Our aim was to determine whether changes in skeletal muscle oxygen saturation (StO₂) measured by near-infrared spectroscopy (NIRS) on the thenar eminence during a vascular occlusion test (VOT) can be used to predict extubation failure from mechanical ventilation.

Methods

We prospectively studied 206 adult patients with acute respiratory failure receiving MV for at least 48 h from a 30-bed mixed ICU, who were deemed ready to wean by their physicians. Patients underwent a 30-min spontaneous breathing trial (SBT), and were extu

SUBMITTER: Mesquida J 

PROVIDER: S-EPMC7214564 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature