The relationship between mean telomere length and blood pressure: results from the National Health and Nutrition Examination Surveys.

ABSTRACT:

Background

Recent studies have shown that telomere length has significantly relationship with different age-related diseases. However, the relationship between mean telomere length (MTL) and elevated blood pressure (BP) has been unclear. Therefore, the aim of the recent study was tried to explore the association of MLT with BP.

Methods

There were 5,981 subjects from the National Health and Nutrition Examination Surveys (NHANES, 1999-2002) was included in analysis. The MTL was measured using the quantitative polymerase chain reaction (PCR) method and expressed in telomere-to-single copy gene (T/S) ratio and grouped into quartiles. Multivariate linear [expressed in beta and 95% confidence interval (CI)], logistic regression [odds ratios (ORs) and 95% CI] analyses and smooth cu

SUBMITTER: Huang YQ 

PROVIDER: S-EPMC7214907 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature