Relationship between sperm morphology and sperm DNA dispersion.

ABSTRACT:

Background

The pathogenesis of teratozoospermia (<4% morphologically normal sperm cells) and the relationship between sperm morphological abnormalities and abnormal sperm nuclear DNA fragmentation, which are considered indicators of male fertility, have not been elucidated. Our research was designed to determine the prevalence of different sperm DNA fragmentation (SDF) levels in men with teratozoospermia and to establish a discriminating threshold value for SDF in assessing sperm morphology.

Methods

Basic semen characteristics and detailed sperm morphological analysis (head, neck, midpiece, and tail defects and excess residual cytoplasm) (WHO, 2010), and the nuclear sperm DNA dispersion test were performed on semen samples obtained from 523 men with teratozoospermia (n=296)

SUBMITTER: Jakubik-Uljasz J 

PROVIDER: S-EPMC7215007 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature