Nomograms to predict the presence and extent of inguinal lymph node metastasis in penile cancer patients with clinically positive lymph nodes.

ABSTRACT:

Background

We developed two nomograms to predict the presence of inguinal lymph node metastasis (ILNM) and two or more histologically positive inguinal lymph nodes (ILNs) or one ILN with extranodal extension (ENE) in penile cancer patients with clinically positive inguinal lymph nodes (ILNs).

Methods

This study enrolled 75 penile squamous cell carcinoma (PSCC) patients with clinically positive ILNs. A binary logistic regression model was taken to screen out the risk factors for the presence of ILNM and two or more positive ILNs or one node with ENE in one side. Nomograms were plotted based on the results of multivariate logistic regression analysis.

Results

Our multivariate analysis demonstrated that the pathological grade, lymphovascular invasion (LVI), and short dia

SUBMITTER: Zhou X 

PROVIDER: S-EPMC7215016 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature