Urinary biomarkers in pelvic-ureteric junction obstruction: a systematic review.

ABSTRACT: Antenatal hydronephrosis is a common finding detected on prenatal ultrasound. Although hydronephrosis will spontaneously resolve in the majority of newborns, there is a significant amount of cases that will worsen with the risk of a progressive and permanent loss of renal function. There is an increasing concern among experts that the current criteria for evaluation of clinically significant obstructions are limited. Our aim is to provide a systematic review of the available literature on biomarkers of renal injury, potential targets for diagnosis and prognosis of children with hydronephrosis. The main search was conducted in the electronic databases from inception through March 2019 using various combinations of the keywords: pelvic-ureteric [All Fields] AND junction [All Fields] AND obst

SUBMITTER: Paraboschi I 

PROVIDER: S-EPMC7215034 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature