"Hydroxychloroquine in patients with COVID-19: A Systematic Review and meta-analysis."

ABSTRACT:

Backgrounds and aims

The role of hydroxychloroquine (HCQ) in the treatment of COVID-19 is not fully known. We studied the efficacy of HCQ compared to the control in COVID-19 subjects on - a. viral clearance measured by reverse transcriptase polymerase chain reaction (RT-PCR) and, b. death due to all cause.

Methods

PubMed, Scopus, Cochrane and MedRxiv database were searched using the specific keywords up to April 30, 2020. Studies that met our objectives were assessed for the risk of bias applying various tools as indicated. Three studies each that reported the outcome of viral clearance by RT-PCR and death due to all cause, were meta-analyzed by applying inverse variance-weighted averages of logarithmic risk ratio (RR) using a random effects model. Heterogeneity and publicat

SUBMITTER: Singh AK 

PROVIDER: S-EPMC7215156 | biostudies-literature | 2020 Jul - Aug

REPOSITORIES: biostudies-literature