Antecedents of epilepsy and seizures among children born at extremely low gestational age.

ABSTRACT: OBJECTIVE:To identify specific risk factors for epilepsy for individuals born extremely preterm. STUDY DESIGN:In a prospective cohort study, at 10-year follow-up, children were classified as having epilepsy or seizures not associated with epilepsy. We evaluated for association of perinatal factors using time-oriented, multinomial logistic regression models. RESULTS:Of the 888 children included in the study, 66 had epilepsy and 39 had seizures not associated with epilepsy. Epilepsy was associated with an indicator of low socioeconomic status, maternal gestational fever, early physiologic instability, postnatal exposure to hydrocortisone, cerebral white matter disease and severe bronchopulmonary dysplasia. Seizure without epilepsy was associated with indicators of placental infection and inf

SUBMITTER: Singh R 

PROVIDER: S-EPMC7216413 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature